33% of 18-25 year olds don't drink, and this ratio is increasing very fast (this percentage is increasing by 3 per year currently). Also, of those who do drink, increasing numbers drink less and it has become "uncool" to get shitfaced amoungst many of this age range.
It's one contributory factor to the loss of lots of pubs, particularly those with nothing of interest to non-drinkers.
Whilst a significant proportion of the non-drinkers have opted for a healthier lifestyle, there is also a proportion who spend that money on drugs now instead of alcohol, due to rising price of alcohol, versus falling price, rising strength and easy availability of drugs, particularly since the ban on legal highs which (predictiably) had the opposite effect to the intent.