I heard something brief about building drawers with pocket screws, but heard none of the details. I thought about it for a few minutes, and this is what I came up with:
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I figure that way none of the screws would show, unless you removed the drawer completely to look at the back. It looks pretty easy too. You could even make the dado for the bottom on the stock before cutting it it to length.
The main drawback that I can think of is being drummed out of the woodworking fraternity for doing something as low class as that. :)
Are there other reasons to avoid it? This is all just speculation at this point, I don't have a particular project in mind. But I hadn't thought of making drawers this way before and it piqued my interest.