Yes you can. However, that will kill stone dead your broadband connection and contract with whoever you're with.
You can migrate fully to Zen for broadband and Digital Voice of course, but their 'Digital Voice' is still a proprietary VoIP service, so essentially just as 'proprietary' as the equivalent Digital Voice BT or Sky offer, so in principle no different to them.
What's needed is the ability to totally uncouple your phone number and/or 'landline service' from your ISP's clutches