I glue up lots of panels. I used to use cauls and biscuits a bunch of
glue, clamp the hell out of them and let them sit 24 hrs in the clamps.
Now I typically spend more time/care getting the edges straight, use
very little glue, clamp lightly and often pop them out in less than two
hours and start working (carefully) with them. Admittadly, I have a
wide belt sander to flatten them but I excercise lots of care in
keeping them flat just by laying them on the table and using a mallet
or my fist to align the edges. Pretty rare that I have any problem.