Irrespective of *where* the fuel is injected (manifold, pre-combustion chamber or direct into cylinder) it is the injection of a dose of fuel as a spray of tiny droplets which determines the moment of combustion - isn't it?
Or are you saying that some engines injected fuel into cool air during the induction stroke, then compressed the fuel-and-air mixture (as opposed to just the air) and let combustion occur when the air had been compressed to a high enough temperature? Didn't that make the timing of combustion extremely variable, without any control over the duration of combustion, whereas injection into the pre-heated air allows a long period of injection to give prolonged burn.