Before you increase ventilation air to solve a chemical buildup problem, yo u might think about two things:
How much ventilation air do you have now? Older houses in the US are not e xactly air tight, especially by European standards. Most leak like sieves. So you need to measure air changes. You need to do that anyway to size A C. Any HVAC company should have the equipment to do this. A door test woul d work, or there are some more sophisticated ones. This isn't expensive.
How much chemical buildup do you have now? There may be none. It could be an allergy or other medical problem. It could even be psychological. Wha t's in the air? Can it be measured? Check humidity too, that affects mold growth. Mold is everywhere and unavoidable, but some people are more sens itive than others. Checking for chemicals is going to be more expensive an d require a specialist, unless you get lucky and have something that shows on a PID.