That depends on the intended use... for most drawers in solid wood
construction nothing but wax on the outside so it glides on the case/guides.
In situations where there is a good chance that the contents will snag
(e.g., knitting, lingerie, etc.) I use dust panels and finish all surfaces
with shellac, sanded smooth, and rubbed out with wax. For utility drawers
made from construction grade sheet goods and installed on slides,
polyurethane to basically glue the surface and edges together.
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