Strangely, I did that earlier this week. And broke some pesky app that looked for a copy of its installation file there - EVERY time you ran it!
It was quite a faff as it wouldn't install again until I'd deinstalled it. And it wouldn't deinstall because the install file wasn't there. (if you're asking why putting the install file back there didn't fix it...it was in a subdirectory with one of those long multi-digit names; I got there in the end)