No, not unless you're going to drill a pilot hole through the OSB for each
screw. When screwing two pieces of wood together, it's important that the
screw threads *not* bite into the first piece: that piece needs to be free to
move along the screw so that the head can draw it tight against the second
piece. That's why wood screws have a smooth shank. Otherwise, if the threads
are biting into *both* pieces at once, the screw can actually hold them a
short distance apart.
Use ring-shank nails.
Doug Miller (alphageek at milmac dot com)
Don't think you need to worry about that with OSB
or chipboard over a denser material, but you still
need a pilot hole in the subfloor (depending on
what is used for the subfloor) and the only way to
do that is to put one through OSB.
Isn't the obvious answer to use deck screws. But
coarse drywall screws to hold OSB to plywood
should work just fine. One would need to be
careful not to strip the hole which would occur
most of the time fore taking the head off the
screw. That isn't true if the subfloor were solid
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