Just wrapped up the first real cold snap with the mini split running in my detached garage shop and I'm honestly relieved at how it handled itself. Space is about 22 by 26 with a 9 foot ceiling, walls and ceiling done properly with insulation, and I heat it to around 60 degrees while I'm out there working weekends. Down to single digits outside last week and the unit never dropped the ball.
The one thing I'd tell anyone shopping for a cold climate setup is to check the low temp operating rating before anything else. A lot of the cheaper units on the big box shelves just aren't meant to run when it gets seriously cold, and the output falls off hard as the temps drop. I paid a bit more upfront for one rated to keep producing heat well below zero and that seems to have been the right call.
I also ran it all winter on a schedule rather than blasting it when I walk in. Keeps the slab warm and the whole space stays usable instead of taking half a day to recover. Summer side has been effortless too, barely breaks a sweat cooling it off after the door's been open all afternoon.