Primed some MDF with Wick's wood primer which appeared to cover normally and left it a day to dry. Colour coat is a B&Q quick dry satin said to be suitable for wood and metal and not to need an undercoat - it's water based. Got a reaction - it formed a series of blobs with the primer not being covered at all between them. I'd used that combination elsewhere on MDF - but not from the same sheet - with success. And on bare whitewood.
A second coat after leaving plenty time for the first to dry produced the same results. I've now rubbed it down and used some undercoat - but will have to wait for that to dry before trying the topcoat again.
Any theories?