Small quantities quickly cause bone destruction. I think it's only a catalyst, so it's not used up in the process and can just cary on going.
Hydrofluoric acid used to be used to make frosted light bulb glass. Glass frosted in this way was very good at diffusing light without generating much loss. It was also possible to etch toughened glass (light bulbs are slightly toughened so they can get away with using very thin glass).
However, even in such carefully controlled industrial processes, handling is now considered too dangerous for this, and they've had to switch to less efficient (in light terms) methods such as powered coatings.