I have vertical redwood siding on one side of my house and I've found that there's a sizeable gap between the bottom edge and the wall that mice have been using to get into my house.
The gap was large enough (1") that I wonder if it's supposed to be there for ventilation.
Here's a pic, but you can hardly tell that there's a gap between the siding and the wall (and, yes, the previous owner painted over beautiful redwood):