From my understanding of MWC's (which could easily be wrong) if the shared neutral fails for any reason, you can potentially end up with much more than
120VAC where you don't want it. If a neutral fails in normally wired pair of outlets, there's usually no risk of voltage escalation or imbalance. However a failer neutral in a MWC can play out like this:There are a couple of other considerations that affect the cost analysis, too. I have always been able to buy 12/2 w/g Romex on sale for much less than 12/3 w/g. So much less, in fact, that there was no difference in the price between running two 12/2 cables and using a MWC using 2/3. I assume that's a function of how much more 12/2 is manufactured than 12/3. It took a little longer to install and staple, but I really prefer separate neutrals. I assume that the different in installation time is a much bigger concern to builders of large tracts of homes.
MWC's require (at least I am pretty sure NEC and CEC say so) a double pole breaker requiring de-energizing both circuits to do repairs. Not a big issue, but at times it's been nice to have a nearby live outlet to plug tools into when I am working on a different circuit in the room. Not sure if the DP breakers with a single handle for MWC's come in "dual skinny" format, either, which is another concern for folks wanting to add new circuits to an older box.
I do have one multiwire circuit in the panel to power my XTB X10 repeater/coupler/amplifier but nothing else is plugged into that outlet, which has about 6' of wire running to the nearby circuit panel. Even that outlet is wired with two separate runs of 12/2 w/g Romex.
I am sure there are labor cost savings for developers building a series of houses, but in my case MWC's didn't make much sense except for the special case of the X10 device that by design has to straddle both hots to communicate between the phases.