If you want it to feel open, maybe you could minimally box in each
obstruction separately. Then, to give them a purpose you could install
glass shelving (and maybe a base cabinet). Top it off with a small can
light or similar above and you could have a beautiful bar look! Also,
you could repeat this idea in the next "bay" over, between the nearest
wall and the first pipe. Throw some wine glasses, scotch glasses and
liquor bottles on there. Voila! You've got a feature for the room!