Since in other threads you are talking about insulation and an attic you have the same options as you would have in most homes.
In Florida with poorly insulated houses, big windows and lots of sun they usually use a quick rule of thumb as a ton (12,000 BTU) per 500 sq ft. With no windows and R-11 insulation in the walls (3.5" fiberglass batts) you should be OK with a ton and a half. The Bard wall hanger somebody mentioned is an option. That is the tall package style unit you see hanging on the side of a building. Another option is a regular split system with the Air handler hanging in the attic or below the ceiling near the center with some duct work distributing the air to the ends of the building.
Are you planning on installing this yourself, do you have a buddy in the trade or are you just calling someone? Other choices are the package unit on the ground with ductwork similar to the split system. This can be DIY since you are just supplying the ducts and the power. It comes fully charged and ready to go in that "package", or the big mini-split which may not be the best air mover but it is the easiest to do and they sell DIY setups for the mini. Move the air with some fans.