Earl has some very good ideas, especially testing the screws and holes on scrap of the wood your project is made of.. gotta remember that one!
What Earl's post reminded me of is that buying a $5 drill index really helped me in choosing/sizing drills/dowels, etc... for example, using Earls' advice, try different screws & drill sizes... but also run your screw through the drill index and see what "drill size" the shank is...
I just had to do that with my plug project.. I had the plugs cut but wasn't sure what hole size they plugged... lol I used the drill index to find that the "small" end of the plug was
21/64, and drilled my holes to that size.. YMMV