I'm not commercial, just hobby type spraying and I spray, maybe, once a month. I seldom spray inside. I can afford to wait until outside conditions are right for the task. I spray down wind or set up an attic fan to draw overspray/fumes away from myself. I don't set up a booth for outside spraying, but I make sure I am not in direct sunlight.
When I have extra large and/or multiple pieces to spray, I often go to a friend's commercial shop, which has an attic fan set up in his dedicated spraying area. The fan creates a draft for drawing overspray/fumes away from the work and out the "window". I suppose this is a standard scenario for commercial guys.
I would think spraying lacquer is nearly as bad as any finish. I spray mostly lacquer. I wear goggles or a shield and a good mask, with pretty good filtering. Right off, I don't know the type/name of the mask I use, but it has a filter on each side of the strapped-on mask. My brother gave this mask to me. It is the type used at his workplace, *Northrop Gruman, Lake Charles, La. *I trust this is a credible reference, as my brother is a supervisor with 30+ yrs experience and I never felt the need to question the mask. My spray area is not near anything that would be affected by any overspray or downwind concerns, so the finish having dyes, additives (?), etc. is not a concern.
Before spraying the project, I practice spraying on the "scrap" temporary back doors of the (incompleted) shop garage, to get my pattern, etc. adjusted correctly. When finished with the project spraying, I use the back doors for spraying the cleaning thinner through the gun, rather than spraying somewhere else (?).... spraying into the environment (polluting the environment).
Sonny