That's what I did with the UFH.
The whole corridor and stairwell is open, has no stat and is entirely heated by the ground floor UFH. This works and since its totally central to the house, I leave it unregulated. I don't hardly run the upstairs conventional heating at all really. Heat rises, bedrooms need to be cooler..
The rest of the ground floor is a pair of connected living/dining rooms, and the master stat is in there.
The only other stat on the UFH is the kitchen because with an Aga in it, it needs to be more or less unheated otherwise, except in depths of arctic blast.
Only heating in the whole house at the moment is the aga, and teh electrical gubbins. Probably about 1.5-2KW in toto.