I recently did some repointing on my house (built around 1900), some of which was behind a rainwater downpipe. The pipe brackets were fixed to the wall using bits of wood wedged between the bricks and nails. I removed these old bits of wood where I wanted to repoint and filled them with mortar. Last night I refixed the pipe brackets to the wall using rawl plugs and screws. After that I took a look at my work from a distance and noticed that the pipe is not quite vertical, or at least not following the vertical line of the adjacent bay window. I don't know if it wasn't straight before but I think I replaced the pipe in its original position, as it seems to sit it the face of the wall correctly (the bricks are gritstone and their surfaces are not level).
I can live with the aesthetics of this as you have to look hard at it to spot it, but... does the pipe need to be perfectly vertical for drainage reasons?