Michael,
Check out the review section of the Home Depot website or something like epinions.com. There do seem to be some brands that hold up better over time.
Like any piece of HVAC equipment it's important to size it correctly. If it runs all the time and doesn't do the job then the capacity isn't enough. However don't go too big as it's the on-off cycles that are tough on them. Newer models seem to run the fan continuously and are more efficient. (Probably still pretty expensive, but that's the price of a wet basement.)
I'm taking care of my wife's uncle's house about 5 hours away. Last month the Realtor called and said the basement was really wet. I brought up our 20-year old GE 40-pint model, ran it for a day and it brought the humidity down into the 50's. There was mold on the floor and a few areas of standing water with humidity in the 70's. The water table is really high and they've had a wet year so far. The sump pump runs frequently even during the Minnesota winter. The good news is that the well will never run dry. I'll see if the dehumidifier is still alive later this month.
Some basements are just built in the wrong place.
dss