to volunteer to have my AC system exploded for science.
LOTS of so-called "drop in replacement" refrigerants are mostly propane. Not that I would recommend using ANY of them on a refrigeration/ac system.
The big problem with propane, in my opinion, is it is a "heavier than air" flammable gas - so if it leaks in your house, and the AC coil/lines are in a asement, the gas may collect rather than disburse, and you have a very real explosion/fire hazard.
Used in an automotive AC system, unless it leaks in your below-grade or basement-connected garage, the hazards are significantly reduced.
If it leaks into the car when you are driving the mercapitan will get you out of the car before it gets dangerous (before it reaches lean explosive limit)