I purchased a Celiera unit on eBay and installed it myself. I am quite happy with it after two years. Most of the systems have pre-charged outdoor units and feature what they called "quick couplers" which are just flared fittings. The installation manual outlines a method to bleed the air out of the lines and indoor unit using a timed purge. This purge is designed to just exhaust the air, and release a minimum of refrigerant. How well it works I cannot attest to.
A friend installed a whole house unit years ago and bought a unit with evacuated lineset and evaporator and true dry-break quick disconnects which did not need to be purged, but I could not locate any.
I had to shorten the lineset so I had to cut and reflare the tubing (I have years of experience at this and all the tools). I do some work on automotive A/C so I have a vacuum pump with the correct fittings which are the same as the mini-split. So I vacuum checked the entire system before releasing the refrigerant instead of using their purge method.
So...yes it can be done if (1) you have the skills and buy a unit with the proper connections and (2) you are satisfied with their purge method. Even though the instructions show this method, reading the fine print reveals that it has to be professionally installed in order to be guaranteed. And if you need a lineset longer than the supplied length, you will have to have it filled anyway, as the refrigerant only fills a certain line length.