Off Topic post dealing with Diabetes

Path: border1.nntp.dca.giganews.com!nntp.giganews.com!newsfeed00.sul.t-online.d e!newsfeed01.sul.t-online.de!t-online.de!fu-berlin.de!uni-berlin.de!indiv idual.net!not-for-mail
Newsgroups: alt.support.diabetes Subject: Artificial sweeteners linked to two fold increase in diabetes Date: Wed, 24 Jun 2009 17:56:20 -0400 Lines: 107
Mime-Version: 1.0 Content-Type: text/plain; charset=windows-1252; format=flowed Content-Transfer-Encoding: 8bit X-Trace: individual.net m169tyU1KZmgdu+90ebE/wvmEkaG3mfcBezt7cW2fPRug8vBAm Cancel-Lock: sha1:/jS5UUPff6I8FFRoLKtqUSSl/7QUser-Agent: Thunderbird 2.0.0.22 (Windows/20090605) Bytes: 5672 Xref: number.nntp.dca.giganews.com alt.support.diabetes:701499
x-no-archive: yes
.......................
This is association, not established causation.
Susan
Artificial Sweeteners Linked to Two-Fold Increase in Diabetes
People who use artificial sweeteners are heavier, more likely to have diabetes, and more likely to be insulin-resistant compared with nonusers. Results show an inverse association between obesity and diabetes, on one side, and daily total caloric, carbohydrate, and fat intake, on the other side, when comparing artificial sweetener users and control subjects.
The association may reflect the increased use of artificial sweeteners by obese and/or diabetic study participants. "This is a cross-section study, so there are limitations we cannot say that artificial sweetener use causes obesity, we can say it is associated with it," stated first author Kristofer S. Gravenstein, a postbaccalaureate researcher with the Clinical Research Branch at the National Institute of Aging (NIA), National Institutes of Health (NIH).
******Artificial sweeteners activate sweet taste receptors in enteroendocrine cells, leading to the release of incretin, which is known to contribute to glucose absorption. Recent epidemiologic studies in Circulation (2008;117:754-761) and Obesity (2008;16:1894-1900) showed an association between diet soda consumption and the development of obesity and metabolic syndrome.*****
This report tested whether participants in the Baltimore Longitudinal Study of Aging (BLSA), which began in 1958, differ in anthropometric measures, daily caloric intake, and glucose status, separating them into three different groups: artificial sweetener users, artificial sweetener nonusers, or controls.
A total of 1,257 participants, with a mean age of 64.8 years (range, 21 - 96 years), had data on self-reported 7-day dietary intake, 2-hour oral glucose tolerance test (OGTT), and anthropometric measures. The major artificial sweetener consumed was aspartame, preferred by 66% of BLSA participants, followed by saccharin (13%), sucralose (1.0%), and combinations of the three (21%).
"In our study, we were actually able to isolate what type of sweetener was used at a certain point in time, as we used food diaries, and not food questionnaires."
"When we first did this analysis, we found that people ate more fat before 1983, which is the year [of] a big increase in artificial sweetener consumption in the American population it was actually when aspartame was approved and diet Coke was introduced," he explained.
******As a result, the study further analyzed data from a subset of participants, starting in 1983. Compared with 550 people who did not use artificial sweeteners, the 443 people who did were younger, heavier, and had a higher body mass index (BMI), yet they did not consume more calories from people who did not use artificial sweeteners. Fat, carbohydrate, protein, and total caloric intake were not different between the two groups (users vs nonusers).******
Furthermore, Mr. Gravenstein noted that people who used artificial sweeteners "were less likely to have a normal OGTT, or they were less likely to be diagnosed as having a normal glucose homeostasis."
In terms of glucose status (the impaired glucose tolerance (IGT), and/or impaired fasting glucose (IFG)) the data show that artificial sweetener users "were not different than the prediabetics, i.e., they had the same prevalence of prediabetes," he said, adding that "in our population, people who used artificial sweeteners were twice as likely to have diabetes, 8.8% compared to 4.4% for controls."
Analyzing the data further, the investigators focused on a subpopulation, in which fasting insulin values were available from 374 nonusers and 311 artificial sweetener users. The users had a higher fasting glucose levels, higher fasting insulin levels, and a higher measure of insulin resistance, as measured by the homeostasis model assessment, but glycosylated hemoglobin A1c levels were similar between the two groups.
The researchers suggest an alternative hypothesis, that artificial sweeteners modulate the metabolic rate through enteroendocrine cells, therefore contributing to the development of diabetes and/or obesity. However, this hypothesis needs further testing in longitudinal analysis and intervention studies, said the investigators.
"Also, it could be that artificial sweeteners are causing diabetes, or it could be that there is a higher use of them because a lot of physicians actually recommend people to use artificial sweeteners to prevent diabetes" Mr. Gravenstein said. The researchers are planning to address this question with a prospective analysis.
Presented at the Annual Meeting of the Endocrine Society: Abstract P2-478. Presented June 11, 2009
--
Garden in shade zone 5 S Jersey USA


http://www.youtube.com/usnationalarchives

  Click to see the full signature.
Add pictures here
<% if( /^image/.test(type) ){ %>
<% } %>
<%-name%>
Add image file
Upload

Snip
I don't have an opinion as to causation but being a diabetic, I can say for certain that the over consumption of diet drinks and artificial sweetners does in fact raise my blood glucose levels. It doesn't seem to matter what kind of sweetner. Prior to being diagnosed as diabetic, I never used artificial sweetners, so at least in my case there was no causation.
The long chain alcohols used to sweeten sugar free candy is no better than cane sugar as far as the effect on blood glucose levels, the packaging for these products encourage their use by diabetics, when in fact they are dangerous.
For true blood sugar control, one must stay away from "all" refined grain products, most rice, all potatoes, eat only raw or what to most people would be undercooked starchy vegatables- if it is white, spit it out. Even 9 of 10 whole wheat breads on the market are padded with sugar and refined flours to the point of making their use for blood glucose control useless.
substituting one poison ( in this case artificial sweetners) for another is just asking for trouble.
As a side note th eworst thing I can eat is a banana
basilisk
Add pictures here
<% if( /^image/.test(type) ){ %>
<% } %>
<%-name%>
Add image file
Upload
wrote: >People who use artificial sweeteners are heavier, more likely to have

... people who are heavier are more likely to drink artificially sweetened foods?

... ALL sweet tasting things bind to "sweet" receptors on the tongue and that is what stimulates insulin. Doesnt matter what the sweetness is. However, non caloric sweeteners dont contribute a form of carbohydrate that has calories.
Recent epidemiologic studies

... the population of people they selected "dietary intake using prospective data from 9514 participants (age, 45 to 64 years) enrolled in the Atherosclerosis Risk in Communities (ARIC) study." are obviously already at risk for diabetes, perhaps due to already having metabolic syndrome and probably high blood pressure. According to the scientists " These prospective findings suggest that consumption of a Western dietary pattern, meat, and fried foods promotes the incidence of MetSyn, whereas dairy consumption provides some protection. The diet soda association was not hypothesized and deserves further study." The diet soda association was not hypothesized and deserves further study." The diet soda association was not hypothesized and deserves further study." Somewhere between zone 5 and 6 tucked along the shore of Lake Michigan on the council grounds of the Fox, Mascouten, Potawatomi, and Winnebago
Add pictures here
<% if( /^image/.test(type) ){ %>
<% } %>
<%-name%>
Add image file
Upload

HomeOwnersHub.com is a website for homeowners and building and maintenance pros. It is not affiliated with any of the manufacturers or service providers discussed here. All logos and trade names are the property of their respective owners.